Creative Biogene is the leading company offering the best recombineering based microbe genome editing services for a large wide range of microorganism species. With the assistance of our excellent scientists and technicians, we will complete your microbe genome editing project in a shot turnaround time with most competitive price. Creative Biogene offers microorganism genome mutation,...

Circular RNAs (circRNAs) are a class of single-stranded, non-coding RNAs which form a covalently closed loop. It was first reported as viroids in plants and was later detected in human cells in 1979. In a circular RNA molecule, unlike a linear RNA, the 5' and 3' ends have been joined together. The unique loop structure of circRNAs provides them with a longer half-life and more resistance to...

MicroRNAs (miRNAs) are a type of small single-stranded non-coding RNA molecules of 18 ~ 24 nucleotide (nt) in length. MiRNAs have been found in many species including plants, animals and some viruses. The conventional biosynthesis pathway consists of four steps: 1) miRNA genes are transcribed by RNA Polymerase II or III to produce pri-miRNAs, 2) pri-miRNAs are recognized and cleaved by...

Purpose of Isolation and Purification of Microorganisms The process of isolation and purification is to obtain only one type or strain of microorganism from a mixed microbial population. In some bacterial assays, we often need to isolate and purify a particular target bacterium because multiple species are often present in the sample. Through isolation and purification, we are able to evaluate...

Filamentous fungi, such as Aspergillus, Trichoderma, and Penicillium species, are considered as unique cell factories for protein production due to the high efficiency of protein secretion and superior capability of post-translational modifications. Many species of filamentous fungi are generally regarded as safe (GRAS). Filamentous fungi have less extensive hyper-mannosylation of...